Secondary active transport

From WikiMD's Food, Medicine & Wellness Encyclopedia

Secondary active transport is a form of active transport across a biological membrane in which a transport protein couples the movement of an ion (typically sodium or hydrogen) down its electrochemical gradient to the movement of another molecule (the "secondary" solute) against its concentration gradient. This process is distinct from primary active transport, where energy from ATP is directly used to transport a solute against its concentration gradient.

Mechanism[edit | edit source]

Secondary active transport brings solute or ions into the cell (or out of the cell) along with the ion that is moving down its electrochemical gradient. The transport protein, or carrier, involved in secondary active transport is a symporter that moves both ions in the same direction, or an antiporter that moves ions in opposite directions.

Types[edit | edit source]

There are two types of secondary active transport:

  • Cotransport (or symport): In cotransport, the direction of the actively transported ion's movement is the same as that of the solute being transported. An example of cotransport is the sodium-glucose transport protein.
  • Countertransport (or antiport): In countertransport, the direction of the actively transported ion's movement is opposite to that of the solute being transported. An example of countertransport is the sodium-calcium exchanger.

Examples[edit | edit source]

Examples of secondary active transport systems include the sodium-potassium pump, the Sodium-calcium exchanger, and the sodium-glucose cotransporter.

See also[edit | edit source]

Secondary active transport Resources
Doctor showing form.jpg
Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Admin, Prab R. Tumpati, MD