5-HIAA

From WikiMD's Food, Medicine & Wellness Encyclopedia

5-HIAA - A substance made by the breakdown of a hormone called serotonin in the liver. Nerves use serotonin to send messages to each other. After 5-HIAA is broken down from serotonin in the liver, the kidneys filter it from the blood and excrete it in the urine. Serotonin and 5-HIAA can increase in patients with certain tumors, such as B. carcinoid tumors, are found in higher than normal amounts. Measuring the amount of 5-HIAA in urine can help diagnose and monitor carcinoid tumors and other diseases. 5-HIAA is a type of tumor marker. Also called 5-hydroxyindoleacetic acid.

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Contributors: Prab R. Tumpati, MD