File:Figure 4 RAD21 Functions in various cellular processes. .tif
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Summary[edit]
| Summary | |
|---|---|
| Description | RAD21 forms cohesin complex with SMC1, SMC3 and STAG1/2 to function in various normal cellular processes (shown in blue). The canonical role of Rad21 is sister chromatid cohesion and separation. Other roles include DNA damage repair, transcription regulation, DNA replication, and centrosome biogenesis, etc. Diseases rise when mutations in RAD21 disrupt its function (in green). Caspase-cleaved Rad21 fragment promotes apoptosis (in purple). REC8 and RAD21L are paralogs of RAD21 in vertebrate, which function specifically to meiosis (in brown). *This Wiki-Gene report on RAD21 is based on a review article “Cohesin Subunit RAD21: from Biology to Disease” by Cheng et al published in Gene |
| Source | Wikimedia Commons file page |
| Author | Scfchenghz |
| Permission | See original Commons license details. |
Licensing[edit]
Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0)
This file is licensed under the Creative Commons Attribution-ShareAlike 4.0 International license.
You are free to:
- Share — copy and redistribute the material.
- Adapt — remix, transform, and build upon the material.
Under the following conditions:
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Official license: CC BY-SA 4.0
License page: CC BY-SA 4.0
Original attribution and file history: Wikimedia Commons
Summary
| Description |
English: RAD21 forms cohesin complex with SMC1, SMC3 and STAG1/2 to function in various normal cellular processes (shown in blue). The canonical role of Rad21 is sister chromatid cohesion and separation. Other roles include DNA damage repair, transcription regulation, DNA replication, and centrosome biogenesis, etc. Diseases rise when mutations in RAD21 disrupt its function (in green). Caspase-cleaved Rad21 fragment promotes apoptosis (in purple). REC8 and RAD21L are paralogs of RAD21 in vertebrate, which function specifically to meiosis (in brown). *This Wiki-Gene report on RAD21 is based on a review article “Cohesin Subunit RAD21: from Biology to Disease” by Cheng et al published in Gene |
| Date | |
| Source | Own work |
| Author | Scfchenghz |
Licensing
I, the copyright holder of this work, hereby publish it under the following license:
This file is licensed under the Creative Commons Attribution-Share Alike 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
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File history
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 22:48, 16 June 2020 |  | 434 × 337 (676 KB) | wikimediacommons>Scfchenghz | Cross-wiki upload from en.wikipedia.org |
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