Grayanotoxins

From WikiMD's Food, Medicine & Wellness Encyclopedia

Grayanotoxins are a group of closely related toxins found in rhododendrons and other plants of the family Ericaceae. They can affect the sodium channels in cell membranes.

History[edit | edit source]

The term "grayanotoxin" was coined in the 1950s, after the American botanist Asa Gray. Grayanotoxins were first isolated and identified in the 1930s.

Sources[edit | edit source]

Grayanotoxins are found in the leaves, flowers, and nectar of some species of the plant family Ericaceae, including Rhododendron, Pieris, Agarista, Leucothoe, Kalmia, Phyllodoce, Menziesia, Ledum, and Zenobia.

Effects[edit | edit source]

Grayanotoxins bind to sodium channels in cell membranes, preventing the normal flow of sodium ions and causing a range of symptoms. These can include nausea, vomiting, salivation, headache, blurred vision, and in severe cases, loss of consciousness, convulsions, and death.

Treatment[edit | edit source]

Treatment for grayanotoxin poisoning is primarily supportive, with intravenous fluids and medications to control symptoms. In severe cases, hospitalization may be required.

See also[edit | edit source]

Grayanotoxins Resources
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Contributors: Prab R. Tumpati, MD