Lamina Propria

Lamina Propria

The Lamina Propria is a thin layer of connective tissue that forms part of the moist linings known as mucous membranes or mucosa, which line various tubes in the body, such as the respiratory tract, the gastrointestinal tract, and the urogenital tract.

Structure

The lamina propria is a component of the mucosa, and thus, it is found in many organs of the body. It is made up of loose connective tissue, and contains various cells, including fibroblasts, macrophages, and mast cells. It also contains blood vessels, lymphatic vessels, and nerves.

Function

The lamina propria serves several functions. It provides support to the epithelium, and also contains the blood vessels and nerves that supply the epithelium. It plays a role in the immune response, as it contains immune cells that can respond to pathogens that penetrate the epithelium. It also allows for flexibility and distension in certain organs, such as the intestines.

Clinical significance

Changes in the lamina propria can be indicative of various diseases. For example, in celiac disease, there is an increase in the number of lymphocytes in the lamina propria. In Crohn's disease, there can be changes in the structure of the lamina propria, including thickening and inflammation.

See also

• Mucous membrane
• Connective tissue
• Epithelium

References

Lamina Propria Resources
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