Drotebanol

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Drotebanol is a synthetic opioid that was developed in the mid-20th century and has been used primarily in the treatment of pain and cough. It is a derivative of morphine, but is more potent and has a longer duration of action.

Etymology[edit | edit source]

The name "Drotebanol" is derived from the chemical name "3-hydroxy-1,2,3,4,5,6-hexahydro-6,6-dimethyl-17-methyl-7,8-didehydro-4,5-epoxy-18,19-dinor-14-methoxy-17-(2-propenyl)morphinan", which describes its chemical structure.

Pharmacology[edit | edit source]

Drotebanol acts primarily as an agonist at the mu-opioid receptor, which is the primary site of action for most opioid drugs. It also has some activity at the kappa-opioid receptor, which may contribute to its analgesic effects. Like other opioids, Drotebanol can produce a range of side effects, including sedation, nausea, constipation, and respiratory depression.

Medical uses[edit | edit source]

Drotebanol has been used in the treatment of both acute and chronic pain, as well as in the suppression of cough. It is typically administered orally, but can also be given by intramuscular injection.

Related terms[edit | edit source]

See also[edit | edit source]

Drotebanol Resources
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Contributors: Prab R. Tumpati, MD