PPAP

PPAP or Platelet-rich plasma is a concentrate of platelet-rich plasma protein derived from whole blood, centrifuged to remove red blood cells. It has a greater concentration of growth factors than whole blood, and has been used to encourage a brisk healing response across several specialties, in particular plastic surgery, dentistry, orthopedics, and dermatology.

History

The use of PRP in medicine started in the 1970s with the production of fibrin glue from patients' own platelets to minimize bleeding during surgery. The use of PRP has expanded in the 1990s to the fields of oral surgery and cosmetic surgery.

Preparation

PRP is prepared by taking blood from the person, and then putting it through two stages of centrifugation designed to separate PRP from platelet-poor plasma and red blood cells. This is usually done by a medical professional.

Uses

PRP has been used in an attempt to treat osteoarthritis, with unclear effect. It has also been used for bone repair and regeneration, in plastic surgery, and in dentistry.

Safety

The safety of PRP is unclear due to the lack of large, high-quality trials. Some safety concerns include the risk of infection if the skin is not properly cleaned before injection, and the risk of injecting into a blood vessel.

See also

• Blood plasma
• Platelet
• Centrifugation

References

PPAP Resources
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