Placebo Effect

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Placebo Effect

The Placebo Effect is a psychological phenomenon where a patient experiences a perceived improvement in their condition due to their belief in the effectiveness of a treatment, rather than the treatment itself having any therapeutic effect. This effect is often observed in clinical trials where a group of patients are given a placebo - a substance with no therapeutic effect - and another group is given the actual medication. The patients who receive the placebo often report improvements in their condition, demonstrating the power of the mind in health and healing.

History[edit | edit source]

The term "placebo" was first used in a medical context in the 18th century and originally referred to a medicine given more to please than to benefit the patient. Over time, the definition has evolved to refer to any treatment that is used for its psychological benefit rather than for any physiological effect.

Mechanism[edit | edit source]

The exact mechanism of the placebo effect is not fully understood. However, it is believed to be related to the patient's expectations and perceptions of how the treatment will affect them. This can be influenced by a variety of factors, including the patient's previous experiences with treatment, their beliefs about the effectiveness of the treatment, and the manner in which the treatment is administered.

Clinical significance[edit | edit source]

The placebo effect has significant implications for clinical trials. It is important to distinguish between the actual effects of a medication and the perceived effects caused by the placebo effect. This is typically done by conducting double-blind trials, where neither the patient nor the doctor knows whether the patient is receiving the actual medication or a placebo.

Criticism and controversy[edit | edit source]

While the placebo effect is widely recognized in the medical community, it is also a source of controversy. Some argue that it is unethical to give patients a placebo without their knowledge, while others argue that the placebo effect can be a powerful tool in treatment.

See also[edit | edit source]

References[edit | edit source]

Placebo Effect Resources
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Contributors: Prab R. Tumpati, MD