Radioactive iodine scan

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Radioactive iodine scan
SynonymsThyroid scan, I-123 scan
PurposeTo diagnose and evaluate thyroid conditions


A radioactive iodine scan, also known as a thyroid scan or I-123 scan, is a medical imaging test used to diagnose and evaluate various thyroid conditions. It involves the use of a small amount of radioactive iodine, which is taken up by the thyroid gland and allows for visualization of its structure and function.

Purpose[edit | edit source]

The primary purpose of a radioactive iodine scan is to assess the function and structure of the thyroid gland. It is commonly used to diagnose and evaluate conditions such as hyperthyroidism, hypothyroidism, thyroid nodules, and thyroid cancer. The scan provides valuable information about the size, shape, and activity of the thyroid gland, helping healthcare professionals make accurate diagnoses and develop appropriate treatment plans.

Procedure[edit | edit source]

The procedure for a radioactive iodine scan typically involves the following steps:

  1. Preparation: Prior to the scan, the patient may be required to follow specific instructions, such as avoiding certain medications or foods that could interfere with the test results. This is to ensure accurate imaging of the thyroid gland.
  1. Administration of radioactive iodine: The patient is given a small amount of radioactive iodine, either orally or through an injection. The iodine is quickly absorbed by the thyroid gland, allowing for its visualization during the scan.
  1. Imaging: After a specific waiting period, typically a few hours to a few days, the patient undergoes imaging using a gamma camera. The camera detects the radiation emitted by the radioactive iodine and creates detailed images of the thyroid gland.
  1. Interpretation: A radiologist or nuclear medicine specialist interprets the images obtained from the scan. They assess the size, shape, and activity of the thyroid gland, looking for any abnormalities or indications of thyroid conditions.

Risks and considerations[edit | edit source]

Radioactive iodine scans are generally safe and well-tolerated. However, there are a few considerations and potential risks associated with the procedure:

  1. Radiation exposure: The use of radioactive iodine involves exposure to ionizing radiation. While the amount of radiation used in a scan is considered safe, precautions are taken to minimize exposure, especially in pregnant women and children.
  1. Allergic reactions: In rare cases, patients may experience an allergic reaction to the radioactive iodine. It is important to inform the healthcare provider of any known allergies or previous adverse reactions to similar substances.
  1. Breastfeeding and pregnancy: Special precautions are necessary for pregnant or breastfeeding women, as the radioactive iodine can be transferred to the fetus or breast milk. In such cases, the benefits and risks of the scan should be carefully evaluated.

Interpretation of results[edit | edit source]

The interpretation of a radioactive iodine scan depends on the specific condition being evaluated. Some common findings include:

  1. Hyperthyroidism: In cases of hyperthyroidism, the scan may reveal increased uptake of radioactive iodine, indicating excessive thyroid activity.
  1. Hypothyroidism: Hypothyroidism is characterized by decreased thyroid function. A radioactive iodine scan may show reduced uptake of the radioactive iodine in such cases.
  1. Thyroid nodules: The scan can help determine whether a thyroid nodule is functioning or non-functioning. Functioning nodules typically show increased uptake, while non-functioning nodules do not.
  1. Thyroid cancer: Radioactive iodine scans are often used to evaluate the extent of thyroid cancer and detect any metastases. Cancerous cells may show abnormal uptake patterns on the scan.

Conclusion[edit | edit source]

A radioactive iodine scan is a valuable diagnostic tool for assessing thyroid function and structure. It provides important information for the diagnosis and management of various thyroid conditions. By visualizing the thyroid gland and evaluating its activity, healthcare professionals can make informed decisions regarding treatment options and patient care.



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Contributors: Prab R. Tumpati, MD