Smell

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Smell is one of the five traditional senses and is also known as olfaction. It is the process by which olfactory receptors in the nasal cavity detect and identify airborne chemicals. The sense of smell plays a crucial role in the detection of hazards, pheromones, and food.

Anatomy and Physiology[edit | edit source]

The primary organ responsible for the sense of smell is the nose. Inside the nasal cavity, there is a specialized region called the olfactory epithelium, which contains olfactory receptor neurons. These neurons have cilia that extend into the nasal mucus and bind to odorant molecules.

When an odorant binds to a receptor, it triggers a signal transduction pathway that results in an electrical signal being sent to the olfactory bulb in the brain. The olfactory bulb processes these signals and sends them to other parts of the brain, including the olfactory cortex, the amygdala, and the hippocampus, which are involved in odor perception, emotional response, and memory, respectively.

Function[edit | edit source]

The sense of smell is essential for various functions, including:

  • Detection of hazards such as smoke, gas leaks, and spoiled food.
  • Identification of food and beverages.
  • Social interactions through the detection of pheromones.
  • Enhancement of the sense of taste.

Disorders of Smell[edit | edit source]

Several conditions can affect the sense of smell, including:

  • Anosmia: Complete loss of smell.
  • Hyposmia: Reduced ability to smell.
  • Parosmia: Distorted perception of smells.
  • Phantosmia: Perception of smells that are not present.

These disorders can result from various causes, such as nasal congestion, head trauma, neurodegenerative diseases like Parkinson's disease and Alzheimer's disease, and exposure to certain chemicals.

Related Pages[edit | edit source]

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD