Subtherapeutic antibiotic use in swine

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Commercial swine production

Subtherapeutic antibiotic use in swine refers to the practice of administering antibiotics to swine at doses below the minimum levels required to treat clinical infections. This practice is primarily aimed at promoting growth and improving feed efficiency in swine populations. Subtherapeutic antibiotic use has been a common practice in the swine industry for several decades, but it has raised significant concerns regarding the development of antibiotic resistance in both animal and human populations.

Overview[edit | edit source]

Subtherapeutic use of antibiotics in swine involves the addition of small quantities of antibiotics to the feed or water of pigs. This is done not to treat illness but rather to prevent disease and promote growth. The antibiotics used can belong to several classes, including tetracyclines, macrolides, and sulfonamides, among others. The practice has been linked to improved feed conversion ratios, meaning that pigs convert feed to body weight more efficiently, and a reduction in the incidence of disease, leading to lower mortality rates and higher productivity in swine herds.

Controversy and Regulation[edit | edit source]

The widespread use of antibiotics in animal agriculture, particularly at subtherapeutic levels, has been a subject of controversy due to its potential role in the development and spread of antibiotic-resistant bacteria. These bacteria can transfer from animals to humans through direct contact, the consumption of contaminated meat, or through the environment. In response to these concerns, regulatory bodies in many countries, including the European Union and the United States, have implemented restrictions or bans on the use of certain antibiotics for growth promotion purposes in livestock.

In the United States, the Food and Drug Administration (FDA) has issued guidelines that require veterinary oversight for the use of medically important antibiotics in feed and water for livestock. These guidelines aim to phase out the use of these antibiotics for growth promotion and to ensure that their use is limited to addressing specific health needs under the supervision of a veterinarian.

Alternatives and Solutions[edit | edit source]

In light of the restrictions on subtherapeutic antibiotic use, the swine industry has been exploring alternative strategies to maintain animal health and productivity. These alternatives include improved animal husbandry practices, such as enhanced biosecurity measures, vaccination programs, and the use of probiotics and prebiotics to support gut health. Additionally, research into the development of new antimicrobial compounds that are less likely to contribute to resistance is ongoing.

Conclusion[edit | edit source]

Subtherapeutic antibiotic use in swine has been a beneficial practice in terms of improving growth and efficiency in pig farming. However, the potential public health risks associated with antibiotic resistance have led to increased regulation and a shift towards alternative strategies for disease prevention and growth promotion in swine production. The swine industry continues to adapt to these changes, seeking to balance productivity with the imperative to protect public health.

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Contributors: Prab R. Tumpati, MD