TCGA

TCGA or The Cancer Genome Atlas is a project that was initiated and managed by the National Cancer Institute and the National Human Genome Research Institute. The project began in 2005 and was completed in 2013. The main goal of TCGA was to improve our understanding of cancer through the application of genome analysis technologies, including large-scale genome sequencing.

Overview

TCGA has generated comprehensive, multi-dimensional maps of the key genomic changes in 33 types of cancer. The project has analyzed the genomes of more than 11,000 patients, which has led to improvements in our ability to diagnose, treat, and prevent cancer. The data generated by TCGA is freely available and has been used by thousands of researchers around the world to make significant discoveries in cancer biology and medicine.

History

The Cancer Genome Atlas project was proposed in 2005 and launched in 2006 with a budget of $50 million. The project was a joint effort between the National Cancer Institute and the National Human Genome Research Institute, two of the 27 institutes and centers that make up the National Institutes of Health (NIH). The project was completed in 2013, but the data it generated continues to be used by researchers.

Impact

The impact of TCGA on cancer research has been significant. The project has led to the discovery of numerous genetic mutations that drive cancer, many of which were previously unknown. These discoveries have led to new treatments and therapies for cancer patients. In addition, the data generated by TCGA has been used to develop new diagnostic tests and to identify patients who are likely to respond to specific treatments.

See also

• National Cancer Institute
• National Human Genome Research Institute
• National Institutes of Health
• Cancer
• Genome sequencing

TCGA Resources
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