Tissue fluid

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Tissue fluid, also known as interstitial fluid, extracellular fluid or cellular fluid, is the fluid that surrounds the cells of the body. It provides the medium for the exchange of substances between the blood and body cells.

Composition[edit | edit source]

Tissue fluid consists of water, inorganic ions, and small solutes such as glucose and amino acids that have been filtered from the blood. It does not contain proteins and cells that are typically found in blood.

Formation[edit | edit source]

Tissue fluid is formed from the blood through the process of filtration. This occurs in the capillaries, where the hydrostatic pressure of the blood forces some plasma to leak out of the capillaries and into the surrounding tissue spaces.

Function[edit | edit source]

The primary function of tissue fluid is to provide a constant environment for the cells of the body. It allows for the exchange of nutrients, oxygen, and waste products between the blood and the cells. It also plays a role in the immune response by transporting white blood cells and antibodies.

Clinical significance[edit | edit source]

Abnormal accumulation of tissue fluid can lead to edema, a condition characterized by swelling of the tissues. This can occur as a result of various medical conditions, including heart failure, kidney disease, and malnutrition.

See also[edit | edit source]

Tissue fluid Resources
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Contributors: Prab R. Tumpati, MD