Torulopsis glabrata

Torulopsis glabrata is a species of yeast that is commonly found in the environment. It is a member of the Candida genus and is known to cause infections in humans, particularly in immunocompromised individuals.

Taxonomy

The yeast was originally classified as Torulopsis glabrata by Heinrich Anton de Bary in 1857. However, it was later reclassified as Candida glabrata due to its ability to form pseudohyphae and its genetic similarity to other species in the Candida genus. Despite this, the name Torulopsis glabrata is still commonly used in the medical literature.

Biology

Torulopsis glabrata is a haploid yeast that reproduces by budding. It is capable of fermenting glucose but not maltose or lactose, which distinguishes it from other species in the Candida genus. It is also resistant to many antifungal drugs, making infections caused by this yeast difficult to treat.

Pathogenicity

Torulopsis glabrata is an opportunistic pathogen, meaning it typically only causes disease in individuals with weakened immune systems. It is a common cause of candidiasis, a type of fungal infection that can affect various parts of the body. Infections caused by T. glabrata are often resistant to treatment with conventional antifungal drugs, making them a significant clinical challenge.

Treatment

Treatment of infections caused by Torulopsis glabrata typically involves the use of antifungal drugs. However, this yeast is known to be resistant to many common antifungals, including fluconazole. As a result, alternative treatments such as echinocandins or amphotericin B may be required.

See also

• Candida (fungus)
• Candidiasis
• Opportunistic infection

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