Zeven

Trade names

Dalvance, Xydalba, Zeven

Other names

Dalbavancin

Dalvance is indicated for acute bacterial skin and skin structure infections (absssi) caused by designated susceptible strains of gram-positive microorganisms.

Usage

To reduce the development of drug-resistant bacteria and maintain the effectiveness of dalvance and other antibacterial drugs, dalvance should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria.

Dosage

• Two-dose regimen: 1000 mg followed one week later by 500 mg
• Dosage adjustment for patients with creatinine clearance less than 30 ml/min and not receiving regularly scheduled hemodialysis: 750 mg followed one week later by 375 mg.

Adminstration

Administer by intravenous infusion over 30 minutes.

Dosage forms and strengths­

For injection: 500 mg of lyophilized powder in a single-use vial for reconstitution

contraindications

Hypersensitivity to dalbavancin

• ­serious hypersensitivity (anaphylactic) and skin reactions have been reported with glycopeptide antibacterial agents, including dalvance; exercise caution in patients with known hypersensitivity to glycopeptides.
• Rapid intravenous infusion of glycopeptide antibacterial agents can cause reactions.
• Alt elevations with dalvance treatment were reported in clinical trials.
• Clostridium difficile-associated diarrhea (cdad) has been reported with nearly all systemic antibacterial agents, including dalvance. Evaluate if diarrhea occurs.

Adverse reactions

The most common adverse reactions in patients treated with dalvance were nausea (5.5%), headache (4.7%), and diarrhea (4.4%).

Drug interactions

No clinical drug-drug interaction studies have been conducted with dalvance. There is minimal potential for drug-drug interactions between dalvance and cytochrome p450 (cyp450) substrates, inhibitors, or inducers

• Dailymed label info on Zeven
• FDA Zeven

Zeven Resources
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Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
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Zeven Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski