OR5AN1

From WikiMD's Food, Medicine & Wellness Encyclopedia

OR5AN1 is a gene that encodes a protein in humans. It is also known as olfactory receptor, family 5, subfamily AN, member 1. This gene is part of the olfactory receptor family, which is the largest gene family in the genome. The olfactory receptors are G protein-coupled receptors that are involved in the detection of smell.

Function[edit | edit source]

The OR5AN1 gene is predominantly expressed in the olfactory epithelium, where it is believed to play a role in the detection of odorants. The protein encoded by this gene is a member of the olfactory receptor family, which is responsible for the detection of odor molecules in the nose. This protein is thought to bind to odor molecules in the nasal cavity and trigger a response in the brain that is perceived as smell.

Structure[edit | edit source]

The OR5AN1 gene is located on chromosome 11 in humans. It spans approximately 3 kilobases and consists of a single coding exon. The protein encoded by this gene is a seven-transmembrane domain protein, characteristic of G protein-coupled receptors.

Clinical significance[edit | edit source]

While the exact role of OR5AN1 in disease is not well understood, it is thought that variations in this gene may be associated with differences in individuals' sense of smell. Further research is needed to fully understand the potential clinical significance of this gene.

See also[edit | edit source]

References[edit | edit source]






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Contributors: Prab R. Tumpati, MD