Α-Methylfentanyl
Α-Methylfentanyl is a potent opioid analgesic drug that is an analog of fentanyl. It was first identified in the mid-1970s in the United States and has been associated with numerous instances of drug overdose.
Chemistry[edit | edit source]
Α-Methylfentanyl, also known as AMF, is a member of the phenylpiperidine class of synthetic opioids. It is structurally related to fentanyl, but differs by the addition of a methyl group on the nitrogen atom. This modification increases the potency of the drug, making it approximately three times stronger than fentanyl.
Pharmacology[edit | edit source]
Like other opioids, Α-Methylfentanyl works by binding to the mu-opioid receptor in the brain, which are responsible for mediating the pain-relieving effects of opioids. However, due to its increased potency, it also carries a higher risk of overdose and death.
Effects[edit | edit source]
The effects of Α-Methylfentanyl are similar to those of other opioids and include pain relief, sedation, and euphoria. However, it also carries a high risk of respiratory depression, which can be fatal.
Legal Status[edit | edit source]
Α-Methylfentanyl is a Schedule I controlled substance in the United States, meaning it has no accepted medical use and a high potential for abuse.
See Also[edit | edit source]
References[edit | edit source]
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