4-HO-McPT

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4-HO-McPT

4-HO-McPT (4-hydroxy-N-methyl-N-cyclopropyltryptamine) is a psychedelic drug that belongs to the tryptamine class of compounds. It is structurally related to other tryptamines such as psilocin (4-HO-DMT), which is the active metabolite of psilocybin mushrooms, and DMT (N,N-Dimethyltryptamine). 4-HO-McPT is known for its psychoactive properties, which can induce altered states of consciousness, visual hallucinations, and changes in thought, mood, and perception in users. The compound is a synthetic substance and is not found in nature.

Chemistry[edit | edit source]

4-HO-McPT is a tryptamine derivative, a family of compounds that share a common molecular structure consisting of a tryptamine backbone. The chemical name for 4-HO-McPT is 4-hydroxy-N-methyl-N-cyclopropyltryptamine. The molecule contains a cyclopropyl group attached to the nitrogen atom of the tryptamine's ethylamine chain, and a hydroxyl group attached to the fourth position of the indole ring. This structural modification is believed to influence the compound's affinity and activity at various neurotransmitter receptors, including the serotonin receptors.

Pharmacology[edit | edit source]

The pharmacological action of 4-HO-McPT, like other psychedelic tryptamines, is primarily attributed to its agonist activity at the 5-HT2A serotonin receptor. However, the exact pharmacological profile of 4-HO-McPT has not been extensively studied, and information on its selectivity, potency, and full spectrum of activity at different serotonin and other neurotransmitter receptors is limited. The presence of the cyclopropyl group may confer unique pharmacokinetic or pharmacodynamic properties compared to other tryptamines, but specific details remain largely speculative.

Effects[edit | edit source]

The effects of 4-HO-McPT are reported to be psychedelic in nature, including visual and auditory hallucinations, enhanced emotional experiences, altered perception of time and space, and introspective insights. The intensity and duration of its effects can vary based on the dose, method of administration, individual physiology, and set and setting. Due to the lack of extensive research and user reports, the full profile of its effects, as well as potential risks and long-term consequences of use, are not well-understood.

Legality[edit | edit source]

The legal status of 4-HO-McPT varies by country and region. In many jurisdictions, it may fall under analogue drug laws due to its structural similarities to controlled substances like psilocin. Users and researchers should consult local regulations and laws regarding the possession, use, and distribution of 4-HO-McPT.

Research and Clinical Potential[edit | edit source]

As of now, there is limited scientific research on 4-HO-McPT. Its potential for therapeutic applications, such as in the treatment of psychiatric disorders or as a tool in psychotherapy, remains speculative and unexplored. Further research could elucidate its pharmacology, safety profile, and possible therapeutic benefits.

See Also[edit | edit source]



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Contributors: Prab R. Tumpati, MD