60S ribosomal protein L21

Ideogram human chromosome 13

60S Ribosomal Protein L21

Structure of 60S ribosomal protein L21

60S ribosomal protein L21 is a protein that in humans is encoded by the RPL21 gene. It is a component of the 60S subunit of the ribosome, which is essential for protein synthesis in cells.

Structure

The 60S ribosomal protein L21 is a ribosomal protein that plays a crucial role in the assembly and function of the ribosome. It is composed of a specific sequence of amino acids that enable it to interact with other ribosomal proteins and RNA molecules within the ribosome.

Function

As a component of the 60S subunit, ribosomal protein L21 participates in the translation process by aiding in the formation of peptide bonds between amino acids during protein synthesis. It also contributes to the overall stability and integrity of the ribosome structure.

Clinical Significance

Mutations in the RPL21 gene encoding 60S ribosomal protein L21 have been associated with certain genetic disorders and diseases. Dysregulation of ribosomal proteins can lead to abnormalities in protein synthesis and cellular functions, potentially contributing to various pathological conditions.

References

1. Smith A, et al. (Year). Title of the paper. Journal Name, Volume(Issue), Page numbers. DOI: [1]