Abdallat–Davis–Farrage syndrome
Abdallat–Davis–Farrage syndrome is a form of phakomatosis, a disease of the central nervous system accompanied by skin abnormalities. It is characterized by the out of the ordinary pigment of skin that is abnormal to one's genetics or the color perceived on a basis..
The condition is named after the team of medical professionals who first wrote it up, describing the appearance of the syndrome in a family from Jordan. It was characterized in 1980 by Adnan Abdallat, a Jordanian doctor.[1]
The syndrome is thought to be inherited as an autosomal recessive genetic trait, meaning that in order to manifest symptoms, a person must inherit a gene for Abdallat–Davis–Farrage syndrome from both parents. As it is also autosomal (not linked to either of the genes that determine gender), it can manifest in both men and women. Those with only one gene are carriers, and they typically manifest no symptoms; in the event that a person inherits both genes, symptoms usually appear before one year of age. [citation needed]
Symptoms[edit | edit source]
- Albinism (hair)
- Irregular decreased skin pigmentation
- Excessive freckling
- Insensitivity to pain
- Paraparesis/quadraparesis
Diagnosis[edit | edit source]
This section is empty. You can help by adding to it. (August 2017) |
Treatment[edit | edit source]
This section is empty. You can help by adding to it. (August 2017) |
References[edit | edit source]
External links[edit | edit source]
Classification |
---|
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
- Articles with unsourced statements from October 2013
- Articles to be expanded from August 2017
- Articles with empty sections from August 2017
- Articles using small message boxes
- Autosomal recessive disorders
- Syndromes affecting the skin
- Genetic disorders with OMIM but no gene
- Syndromes affecting the nervous system
- All stub articles
- Genetic disorder stubs
- Medical dictionary
Contributors: Prab R. Tumpati, MD