Actinium(III) fluoride

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Actinium(III) fluoride (AcF3) is an inorganic compound composed of actinium, a rare earth element, and fluorine, a halogen. This compound is part of the actinide series in the periodic table and exhibits the common oxidation state of +3 for actinium. Actinium(III) fluoride is one of the few known compounds of actinium, a radioactive element that has limited availability and few practical applications due to its radioactivity.

Properties[edit | edit source]

Actinium(III) fluoride is a white solid under normal conditions. It is highly radioactive due to the presence of actinium, which has no stable isotopes. The compound is insoluble in water, a characteristic typical of many fluoride compounds of the actinide series. Its chemical and physical properties are not well-characterized due to the scarcity of actinium and the challenges associated with handling radioactive materials.

Synthesis[edit | edit source]

The synthesis of Actinium(III) fluoride involves the reaction of actinium metal with fluorine gas. This process requires careful control of conditions due to the high reactivity of fluorine and the radioactivity of actinium:

\[ \text{2 Ac} + \text{3 F}_2 \rightarrow \text{2 AcF}_3 \]

Due to the limited availability of actinium, this synthesis is typically carried out in specialized laboratories equipped to handle radioactive materials safely.

Applications[edit | edit source]

The applications of Actinium(III) fluoride are primarily research-oriented, focusing on the study of actinium's chemical properties and its potential uses in nuclear medicine. Actinium-225, an isotope of actinium, has shown promise in targeted alpha therapy (TAT), a type of radiation therapy for treating cancer. However, the use of Actinium(III) fluoride in these applications is limited by the availability of actinium and the challenges associated with its radioactivity.

Safety[edit | edit source]

Handling Actinium(III) fluoride requires strict safety measures due to its radioactivity and the toxicity of fluorine gas. Safety protocols include the use of glove boxes, ventilation, and protective clothing to minimize exposure to radiation and prevent inhalation or ingestion of radioactive particles.

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Contributors: Prab R. Tumpati, MD