Anileridine hydrochloride

Anileridine Hydrochloride is a synthetic opioid analgesic drug, chemically classified as a piperidine derivative. It is primarily used in the management of moderate to severe pain.

Chemistry

Anileridine Hydrochloride is a white crystalline powder with the chemical formula C22H28N2O3.HCl. It is soluble in water and has a pKa of 8.9. The compound is a synthetic opioid, meaning it is made in a laboratory and is not derived from natural sources like the opium poppy.

Pharmacology

Anileridine Hydrochloride works by binding to the mu-opioid receptor in the central nervous system. This binding action inhibits the transmission of pain signals, thereby reducing the perception of pain. The drug has a rapid onset of action, with peak effects occurring within 15 to 30 minutes after administration.

Clinical Use

Anileridine Hydrochloride is used for the management of moderate to severe pain. It is often used in post-operative pain management, or for pain associated with trauma or cancer. The drug is typically administered via injection.

Side Effects

Common side effects of Anileridine Hydrochloride include nausea, vomiting, constipation, and drowsiness. More serious side effects can include respiratory depression, hypotension, and dependence.

Regulation

In the United States, Anileridine Hydrochloride is classified as a Schedule II controlled substance by the Drug Enforcement Administration (DEA), indicating that it has a high potential for abuse and dependence.

See Also

• Opioid
• Mu-opioid receptor
• Drug Enforcement Administration