Blocking agent

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Blocking agent is a term used in various fields of science and medicine, referring to a substance that inhibits the function of certain biological processes. In pharmacology, a blocking agent, also known as an antagonist, is a drug that inhibits the action of certain receptors or enzymes in the body. In biochemistry, a blocking agent is a substance that prevents non-specific binding of other molecules.

Pharmacology[edit | edit source]

In pharmacology, a blocking agent is a type of drug that inhibits the action of certain receptors or enzymes in the body. These drugs are often used to treat various medical conditions by blocking the action of natural substances that may cause harm or discomfort. For example, beta blockers are a type of blocking agent that inhibits the action of adrenaline on the heart and blood vessels, reducing blood pressure and heart rate.

Biochemistry[edit | edit source]

In biochemistry, a blocking agent is a substance that prevents non-specific binding of other molecules. This is often used in techniques such as western blotting and immunohistochemistry, where a blocking agent is used to prevent antibodies from binding to areas of the sample that are not of interest. This helps to reduce background noise and improve the specificity of the technique.

Types of Blocking Agents[edit | edit source]

There are various types of blocking agents used in different fields. Some of the most common include:

  • Beta blockers: These are drugs that block the action of adrenaline on the heart and blood vessels, reducing blood pressure and heart rate.
  • Calcium channel blockers: These drugs block the movement of calcium into cells, which can help to relax the muscles and reduce blood pressure.
  • Enzyme inhibitors: These are substances that block the action of enzymes, preventing them from carrying out their normal function.
  • Antibody blocking agents: These are substances used in biochemistry to prevent non-specific binding of antibodies.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD