CYP2W1

CYP2W1 is a gene that encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 7. This endoplasmic reticulum membrane protein is expressed in the brain and in tumors of the colon, ovaries, and esophagus, suggesting its involvement in central nervous system development and carcinogenesis in these tissues.

Function

CYP2W1 is a member of the cytochrome P450 family of enzymes, which are involved in the metabolism of a wide variety of substances, including drugs, toxins, and endogenous compounds. The specific function of CYP2W1 is not well understood, but it is thought to play a role in the metabolism of certain drugs and toxins.

Clinical significance

CYP2W1 has been found to be overexpressed in several types of cancer, including colon cancer, ovarian cancer, and esophageal cancer. This overexpression may contribute to the development and progression of these cancers. In addition, variations in the CYP2W1 gene may influence an individual's response to certain drugs, potentially affecting drug efficacy and toxicity.

Research

Research into the function and clinical significance of CYP2W1 is ongoing. Current areas of focus include the role of CYP2W1 in drug metabolism and cancer development, as well as the potential use of CYP2W1 as a biomarker for certain types of cancer.

See also

• Cytochrome P450
• Gene
• Enzyme
• Cancer

References

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