Carbo-mer

From WikiMD's Food, Medicine & Wellness Encyclopedia

Carbomer is a term used for a series of polymers primarily made from acrylic acid. Carbomers are white, fluffy powders but are frequently used in cosmetics and personal care products as thickening agents, gelling agents, or as emulsifiers. They have the ability to absorb and retain water, and can swell up to many times their original volume when dispersed in water. This property makes them useful in a wide range of products, including gels, creams, and lotions.

Properties and Uses[edit | edit source]

Carbomers are synthetic polymers that can absorb large amounts of water, leading to their significant swelling in aqueous solutions and forming a gel. This gel-forming ability is what makes carbomers valuable in the formulation of personal care products and pharmaceuticals. They provide a smooth texture to creams and lotions, offer a stabilizing effect for emulsions, and improve the viscosity and flow properties of cosmetic products.

In the pharmaceutical industry, carbomers are used as excipients in the formulation of tablets, suspensions, ointments, and gels. They serve as controlled-release agents, bioadhesion agents, and are involved in drug stabilization.

Chemistry[edit | edit source]

Carbomers are derived from the polymerization of acrylic acid and cross-linking with an allyl ether of pentaerythritol, an allyl ether of sucrose, or an allyl ether of propylene. The molecular weight of carbomers can vary greatly, influencing their gel strength and viscosity. The specific type of carbomer is denoted by a number following the generic term, such as Carbomer 940 or Carbomer 980, indicating different molecular weights and properties.

Safety and Regulatory Status[edit | edit source]

Carbomers are considered safe for use in cosmetic and personal care products. They are approved by regulatory agencies such as the U.S. Food and Drug Administration (FDA) and the European Union for use in over-the-counter pharmaceutical formulations. Despite their synthetic origin, carbomers do not penetrate the skin due to their large molecular size, reducing concerns over systemic toxicity.

Environmental Considerations[edit | edit source]

While carbomers are not known to be harmful to the environment, their synthetic nature and persistence raise questions about their biodegradability. Research into environmentally friendly alternatives and biodegradable polymers is ongoing to address these concerns.

Conclusion[edit | edit source]

Carbomers play a crucial role in the formulation of various cosmetic, personal care, and pharmaceutical products. Their ability to modify viscosity, stabilize emulsions, and control drug release makes them invaluable in many applications. Despite their benefits, ongoing research into their environmental impact and potential alternatives is essential to ensure sustainable use.

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Contributors: Prab R. Tumpati, MD