Dermcidin

Dermcidin is an antimicrobial peptide that is produced by human sweat glands. It was first identified in 2001 and is known to play a crucial role in the immune system's first line of defense against pathogens.

Function

Dermcidin is secreted into sweat and transported to the skin's surface, where it provides protection against invading microorganisms. It is effective against a broad range of bacteria, including E. coli, E. faecalis, S. aureus, and C. albicans.

Unlike other antimicrobial peptides, dermcidin does not rely on membrane disruption to kill bacteria. Instead, it forms channels in the bacterial membrane, which leads to an imbalance in ion concentrations and ultimately cell death.

Clinical significance

Dermcidin may have potential therapeutic applications, particularly in the treatment of antibiotic-resistant infections. However, more research is needed to fully understand its mechanisms of action and potential uses in medicine.

See also

• Antimicrobial peptides
• Sweat glands
• Immune system

References

Dermcidin Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski