Multiple minute digitate hyperkeratosis

Multiple minute digitate hyperkeratosis' (MMDH) is a rare skin disorder characterized by the presence of numerous small, finger-like projections of hyperkeratotic skin. These projections typically appear on the trunk, extremities, and occasionally on the face. The condition is benign but can be cosmetically concerning for affected individuals.

Presentation[edit | edit source]

MMDH usually presents in adulthood, although cases in children have been reported. The hyperkeratotic projections are typically 1-5 mm in length and can be either skin-colored or slightly pigmented. They are often asymptomatic but can sometimes cause mild itching or discomfort.

Etiology[edit | edit source]

The exact cause of MMDH is unknown. It is believed to be a sporadic condition, although some cases suggest a possible genetic predisposition. There is no known association with other systemic diseases.

Diagnosis[edit | edit source]

The diagnosis of MMDH is primarily clinical, based on the characteristic appearance of the skin lesions. A skin biopsy may be performed to confirm the diagnosis, revealing hyperkeratosis and acanthosis without significant inflammation.

Differential Diagnosis[edit | edit source]

Conditions that may resemble MMDH include:

Treatment[edit | edit source]

There is no definitive cure for MMDH, but various treatments can help manage the condition. These include:

Topical keratolytics such as salicylic acid or urea
Topical retinoids
Cryotherapy
Laser therapy

Prognosis[edit | edit source]

MMDH is a chronic condition that tends to persist over time. However, it is benign and does not lead to serious health problems. Treatment can improve the appearance of the skin but may need to be ongoing to maintain results.