IL-3

IL-3 is a type of interleukin that is produced by T cells following cell activation by antigens. IL-3 is capable of supporting the growth and differentiation of T cells, B cells, mast cells, eosinophils, megakaryocytes, and granulocytes. In the immune system, IL-3 tends to be produced by T cells and mast cells.

Function

IL-3 stimulates the differentiation of multipotent hematopoietic stem cells into myeloid progenitor cells or, with other factors such as IL-7, into lymphoid progenitor cells. It is secreted by basophils and activated T cells to support growth and differentiation of T cells from the bone marrow in an immune response.

Clinical Significance

IL-3 has been associated with several autoimmune diseases, including rheumatoid arthritis, psoriasis, and multiple sclerosis. It is also involved in various biological processes, including allergy, asthma, and cancer.

See Also

• Interleukin
• T cells
• B cells
• Mast cells
• Eosinophils
• Megakaryocytes
• Granulocytes
• Hematopoietic stem cells
• Myeloid
• Lymphoid
• Autoimmune diseases
• Rheumatoid arthritis
• Psoriasis
• Multiple sclerosis
• Allergy
• Asthma
• Cancer

IL-3 Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski