Isolated superior mesenteric artery dissection

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Superior mesenteric a

Isolated superior mesenteric artery dissection

Isolated superior mesenteric artery dissection (ISMAD) is a rare condition characterized by the separation of the layers of the superior mesenteric artery (SMA) wall. The SMA is a major blood vessel that supplies blood to the small intestine, cecum, and ascending colon. ISMAD can lead to a variety of symptoms, including severe abdominal pain, nausea, vomiting, and diarrhea.

Symptoms[edit | edit source]

Patients with ISMAD often present with sudden and severe abdominal pain, which may be localized to the mid-abdomen or right lower quadrant. Other common symptoms include nausea, vomiting, and diarrhea. In some cases, patients may also experience fever and signs of peritoneal irritation.

Diagnosis[edit | edit source]

The diagnosis of ISMAD is typically made using imaging studies such as CT angiography or magnetic resonance angiography (MRA). These tests can help visualize the dissection and assess the extent of the damage to the SMA. In some cases, a duplex ultrasound may also be used to evaluate blood flow in the affected artery.

Treatment[edit | edit source]

The management of ISMAD depends on the severity of the dissection and the presence of complications. In mild cases, conservative treatment with pain management and close monitoring may be sufficient. However, in more severe cases or in the presence of complications such as bowel ischemia, surgical intervention may be necessary. Surgical options include endarterectomy, bypass surgery, or stent placement.

Prognosis[edit | edit source]

The prognosis for patients with ISMAD varies depending on the extent of the dissection and the timeliness of treatment. With prompt diagnosis and appropriate management, many patients can achieve a good outcome. However, delayed diagnosis or inadequate treatment can lead to serious complications such as bowel infarction and death.


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Contributors: Prab R. Tumpati, MD