KIZ (gene)

KIZ is a gene that encodes a protein in humans. The KIZ gene is also known as PLK1S1, and it is located on chromosome 1.

Function

The KIZ gene encodes a protein that is involved in the regulation of cell cycles. It is particularly important in the process of mitosis, where it plays a role in the formation of the spindle apparatus. The protein encoded by the KIZ gene interacts with PLK1, a protein kinase that is crucial for cell division.

Clinical significance

Mutations in the KIZ gene have been associated with certain medical conditions. For example, a mutation in this gene can lead to autosomal recessive retinitis pigmentosa, a type of eye disease that causes progressive vision loss.

Research

Research into the KIZ gene and its associated protein continues to be an active area of study. Understanding the function and regulation of this gene could have implications for the development of new treatments for diseases associated with cell cycle dysregulation, such as cancer.

See also

• List of genes
• Human genome
• Cell cycle
• Mitosis
• Retinitis pigmentosa

References

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