L-687,384

From WikiMD's Food, Medicine & Wellness Encyclopedia

L-687,384 is a pharmacological compound that acts as a protease inhibitor. It is specifically a HIV protease inhibitor, which means it is used in the treatment of HIV and AIDS.

Mechanism of Action[edit | edit source]

L-687,384 works by inhibiting the action of the HIV-1 protease, an enzyme that is necessary for the virus to replicate within the body. By blocking this enzyme, L-687,384 prevents the virus from multiplying, thereby slowing the progression of the disease.

Pharmacokinetics[edit | edit source]

The pharmacokinetics of L-687,384 involve its absorption, distribution, metabolism, and excretion in the body. Like other protease inhibitors, it is typically taken orally and is absorbed in the gastrointestinal tract. It is then distributed throughout the body, where it inhibits the action of the HIV-1 protease.

Side Effects[edit | edit source]

As with any medication, L-687,384 can cause side effects. These may include nausea, diarrhea, and changes in body fat distribution. It is important for patients to discuss these potential side effects with their healthcare provider before starting treatment.

Drug Interactions[edit | edit source]

L-687,384 may interact with other medications, including other antiretroviral drugs. These interactions can affect the effectiveness of the medications and may increase the risk of side effects. Therefore, it is crucial for patients to inform their healthcare provider of all medications they are currently taking.

Research and Development[edit | edit source]

L-687,384 was developed as part of a larger effort to find effective treatments for HIV and AIDS. While it has shown promise in laboratory studies, further research is needed to determine its long-term effectiveness and safety in humans.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD