LRG1

LRG1 (Leucine-rich alpha-2-glycoprotein 1) is a protein that in humans is encoded by the LRG1 gene. It is a secreted protein that is involved in various biological processes, including cell migration, angiogenesis, and inflammation.

Function

LRG1 is a secreted protein that is involved in various biological processes. It is known to play a role in cell migration, angiogenesis, and inflammation. LRG1 has been found to be upregulated in several types of cancer, including colorectal cancer, ovarian cancer, and lung cancer. It is thought to promote tumor growth and metastasis by enhancing angiogenesis and cell migration.

Clinical significance

LRG1 has been identified as a potential biomarker for several types of cancer. Studies have shown that high levels of LRG1 in the blood can be indicative of colorectal cancer, ovarian cancer, and lung cancer. In addition to its role in cancer, LRG1 has also been implicated in other diseases, such as age-related macular degeneration and diabetic retinopathy.

Research

Research into LRG1 is ongoing, with studies focusing on its role in disease progression and its potential as a therapeutic target. Some studies are investigating the possibility of using LRG1 as a target for cancer therapy, while others are exploring its role in eye disease.

See also

• Leucine-rich repeat
• Glycoprotein
• Angiogenesis
• Cell migration

References

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