List of life extension related topics

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List of Life Extension Related Topics

Life extension science, also known as anti-aging medicine, indefinite life extension, or biogerontology, has emerged as a multidisciplinary field aiming to slow down or reverse the processes of aging to extend both the maximum and average lifespan. The pursuit of life extension is supported by various technologies and scientific disciplines such as gerontology, regenerative medicine, and genetic engineering. This article provides an overview of key topics and areas of research within the field of life extension.

Biogerontology[edit | edit source]

Biogerontology is the sub-field of gerontology concerned with the biological processes of aging. Researchers in this field study the underlying mechanisms of aging with the aim of developing interventions that can delay or prevent age-related decline.

Regenerative Medicine[edit | edit source]

Regenerative Medicine focuses on repairing, replacing, or regenerating human cells, tissues, or organs to restore or establish normal function. This includes the use of techniques like stem cell therapy and tissue engineering, which are pivotal in addressing age-related damage and diseases.

Genetic Engineering[edit | edit source]

Genetic Engineering in the context of life extension involves modifying the genetic material of an organism to achieve a beneficial outcome. This can include gene therapy techniques aimed at correcting genetic disorders that contribute to aging or enhancing genes that protect against aging.

Caloric Restriction[edit | edit source]

Caloric Restriction is a dietary regimen that reduces calorie intake without incurring malnutrition. Research has shown that caloric restriction can extend lifespan in various animal models, and studies are ongoing to understand its effects on humans.

Cryonics[edit | edit source]

Cryonics is the low-temperature preservation of human bodies, with the hope that resuscitation and restoration to full health may be possible in the future. Cryonics is based on the premise that future medical technology could allow for the revival of individuals and the treatment of diseases that are untreatable by current means.

Nootropics[edit | edit source]

Nootropics, also known as smart drugs or cognitive enhancers, are substances that purportedly improve cognitive function. While primarily used for improving memory, focus, and cognitive ability, some also believe in their potential for extending lifespan by protecting the brain from age-related decline.

Senolytics[edit | edit source]

Senolytics are a class of drugs that specifically target and eliminate senescent cells. Senescent cells are cells that have stopped dividing and contribute to aging and age-related diseases. By removing these cells, senolytics aim to reduce the negative impacts of aging.

Telomerase Therapy[edit | edit source]

Telomerase Therapy involves the activation of the enzyme telomerase, which can extend the telomeres at the ends of chromosomes. Telomeres shorten with each cell division, and their length is associated with lifespan. By extending telomeres, this therapy aims to slow down or reverse cellular aging.

Nutraceuticals[edit | edit source]

Nutraceuticals are food-derived products that offer health and medical benefits, including the prevention and treatment of disease. Certain nutraceuticals are believed to have anti-aging properties by providing the body with essential nutrients that support overall health and longevity.

Futurism and Transhumanism[edit | edit source]

Futurism and Transhumanism are philosophical and social movements that explore the potential for future advancements in technology, including life extension, to enhance human capabilities and improve the human condition.


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Contributors: Prab R. Tumpati, MD