Lufotrelvir
Lufotrelvir is an antiviral drug that is currently under investigation for the treatment of COVID-19. It is a prodrug of remdesivir, which means it is metabolically converted into the active drug remdesivir in the body.
Mechanism of Action[edit | edit source]
Lufotrelvir works by inhibiting the RNA-dependent RNA polymerase (RdRp) of the SARS-CoV-2 virus. RdRp is an essential enzyme for the replication of the virus. By inhibiting this enzyme, lufotrelvir prevents the virus from multiplying in the body.
Clinical Trials[edit | edit source]
Lufotrelvir is currently being tested in clinical trials for the treatment of COVID-19. Preliminary results have shown promise, but more research is needed to confirm its efficacy and safety.
Side Effects[edit | edit source]
As with any medication, lufotrelvir may cause side effects. These can include nausea, vomiting, and diarrhea. More serious side effects can include liver damage and allergic reactions.
Contraindications[edit | edit source]
Lufotrelvir should not be used in patients with a known allergy to remdesivir or any of its components. It should also be used with caution in patients with liver disease.
See Also[edit | edit source]
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