MIR7-1
MIR7-1 is a gene that in humans is encoded by the MIR7-1 microRNA precursor. MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression at the post-transcriptional level, playing a key role in various biological processes such as development, differentiation, apoptosis, and proliferation.
Function[edit | edit source]
The MIR7-1 gene is part of the microRNA family, which are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. MIR7-1 functions as a tumor suppressor in various types of cancer, including breast cancer, lung cancer, and glioma. It is also involved in the regulation of the insulin signaling pathway.
Clinical significance[edit | edit source]
Alterations in the expression of MIR7-1 have been associated with various types of cancer. For example, downregulation of MIR7-1 has been observed in glioblastoma multiforme, the most common and aggressive type of primary brain tumor. In addition, MIR7-1 has been implicated in the development of resistance to cancer treatments.
Research[edit | edit source]
Research into the role of MIR7-1 in cancer and other diseases is ongoing. Understanding the function of this gene and its role in disease could lead to the development of new therapeutic strategies.
See also[edit | edit source]
References[edit | edit source]
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Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.Contributors: Prab R. Tumpati, MD