Methdilazine hydrochloride

From WikiMD's Food, Medicine & Wellness Encyclopedia

Methdilazine Hydrochloride is a type of antihistamine used in the treatment of various allergic reactions. It is a member of the phenothiazine class of antihistamines and is primarily used to alleviate symptoms of allergies such as itching, rash, and hives.

Pharmacology[edit | edit source]

Methdilazine Hydrochloride works by blocking the effects of histamine, a substance in the body that causes allergic symptoms. It is a competitive antagonist of histamine H1 receptors, which means it prevents histamine from binding to these receptors and causing symptoms of an allergic reaction.

Uses[edit | edit source]

Methdilazine Hydrochloride is used to treat a variety of allergic conditions, including urticaria, rhinitis, and dermatitis. It can also be used to alleviate the symptoms of the common cold and influenza, as well as in the treatment of nausea and vomiting.

Side Effects[edit | edit source]

Like all medications, Methdilazine Hydrochloride can cause side effects. These may include drowsiness, dry mouth, blurred vision, and constipation. In rare cases, it can cause serious side effects such as tachycardia, hypotension, and extrapyramidal symptoms.

Precautions[edit | edit source]

Patients with a history of glaucoma, prostate problems, or urinary retention should use Methdilazine Hydrochloride with caution. It should not be used in patients with a known hypersensitivity to phenothiazines.

Interactions[edit | edit source]

Methdilazine Hydrochloride can interact with other medications, including MAO inhibitors, anticholinergic drugs, and CNS depressants. It is important to inform your healthcare provider of all medications you are currently taking before starting treatment with Methdilazine Hydrochloride.


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Contributors: Prab R. Tumpati, MD