Micronodular basal cell carcinoma

Micronodular basal cell carcinoma (MBCC) is a subtype of basal cell carcinoma (BCC), which is the most common form of skin cancer. MBCC is characterized by its small, nodular growth pattern and is known for its aggressive behavior compared to other BCC subtypes.

Epidemiology

MBCC is relatively rare, accounting for approximately 1-2% of all BCC cases. It is more common in older individuals and those with fair skin, although it can occur in people of all skin types. Like other forms of BCC, MBCC is associated with exposure to ultraviolet (UV) radiation, particularly intermittent, intense sun exposure.

Clinical Presentation

MBCC typically presents as small, flesh-colored or pink nodules on the skin. These nodules may be smooth or warty in appearance and are often mistaken for benign skin lesions such as seborrheic keratosis or dermatofibroma. Unlike other BCC subtypes, MBCC does not typically present with the classic signs of BCC such as ulceration or telangiectasia.

Diagnosis

The diagnosis of MBCC is typically made through skin biopsy, where a small sample of the lesion is removed and examined under a microscope. The characteristic histological feature of MBCC is the presence of multiple small nests of basaloid cells in the dermis, which distinguishes it from other BCC subtypes.

Treatment

The treatment of MBCC typically involves surgical removal of the lesion. Due to the aggressive nature of MBCC, a wider margin of normal skin is often removed compared to other BCC subtypes. In cases where surgery is not possible, other treatments such as radiation therapy or topical chemotherapy may be used.

Prognosis

While MBCC is more aggressive than other BCC subtypes, the overall prognosis is generally good as it rarely metastasizes. However, due to its aggressive nature, there is a higher risk of local recurrence compared to other BCC subtypes.

See Also

• Basal cell carcinoma
• Skin cancer
• Dermatology

This skin cancer related article is a stub.

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