Mossy fiber (cerebellum)

Mossy fiber (cerebellum)

File:Mossy fiber cerebellum.jpg

Mossy fibers in the cerebellum

The mossy fiber is a type of neuron that is primarily found in the cerebellum. It is one of the two main types of input fibers that transmit sensory and motor information to the cerebellum, the other being the climbing fiber.

Structure

Mossy fibers originate from various regions of the brain and spinal cord, including the pons, the spinal cord, and the inferior olivary nucleus. They enter the cerebellum via the middle cerebellar peduncle and branch out extensively to form a complex network of fibers.

Function

Mossy fibers transmit information to the cerebellum about the body's position and movement, as well as sensory information from the environment. They synapse with the granule cells in the cerebellar cortex, which in turn send signals to the Purkinje cells, the main output neurons of the cerebellum.

Clinical significance

Abnormalities in the mossy fibers can lead to various neurological disorders, such as ataxia, tremor, and dysmetria. Research is ongoing to understand the role of mossy fibers in these conditions and to develop potential treatments.

See also

• Cerebellum
• Neuron
• Climbing fiber
• Granule cell
• Purkinje cell

References

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