N-hydroxyphthalimide

N-Hydroxyphthalimide (NHPI) is a chemical compound that is commonly used in various scientific and industrial applications. It is a white crystalline solid that is soluble in polar organic solvents.

Structure and Properties

N-Hydroxyphthalimide is a derivative of phthalimide, which is itself a derivative of phthalic anhydride. The compound consists of a phthalimide group, which is a six-membered ring containing two nitrogen atoms, and a hydroxy group, which is an oxygen atom bonded to a hydrogen atom. The presence of the hydroxy group makes the compound more polar and therefore more soluble in polar solvents.

The molecular formula of N-Hydroxyphthalimide is C8H5NO3, and its molar mass is 165.13 g/mol. It has a melting point of 210-213 °C and a boiling point of 360.6 °C at 760 mmHg.

Applications

N-Hydroxyphthalimide is used in a variety of applications in the scientific and industrial fields. One of its most common uses is as a catalyst in the oxidation of alkanes to alcohols, a process that is important in the production of various chemicals. It is also used in the synthesis of pharmaceuticals and other organic compounds.

In addition to its use as a catalyst, N-Hydroxyphthalimide has been studied for its potential use in the treatment of certain medical conditions. For example, it has been shown to have anti-inflammatory and anti-cancer properties, although more research is needed in this area.

Safety and Precautions

Like many chemical compounds, N-Hydroxyphthalimide should be handled with care. It can cause skin and eye irritation, and it may be harmful if swallowed or inhaled. Therefore, it should be used only in a well-ventilated area and with appropriate protective equipment.

See Also

• Phthalimide
• Phthalic anhydride
• Organic chemistry
• Catalysis

References

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