Ototoxic medication

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Ototoxic Medication

An ototoxic medication is a type of drug that has the potential to cause damage to the structures of the inner ear, leading to hearing loss or balance problems. These medications can affect the delicate hair cells in the cochlea or the vestibular system, resulting in temporary or permanent hearing impairment.

Causes[edit | edit source]

Ototoxic medications can include certain antibiotics, chemotherapy drugs, loop diuretics, and nonsteroidal anti-inflammatory drugs (NSAIDs). These medications can damage the hair cells in the inner ear, leading to hearing loss, tinnitus, or vertigo.

Symptoms[edit | edit source]

Symptoms of ototoxicity may include hearing loss, ringing in the ears, dizziness, and balance problems. These symptoms can vary depending on the type and dosage of the medication, as well as individual susceptibility.

Treatment[edit | edit source]

Treatment for ototoxicity involves discontinuing the use of the offending medication if possible. In some cases, hearing aids or cochlear implants may be recommended to help manage hearing loss. Vestibular rehabilitation therapy can also be beneficial for balance issues.

Prevention[edit | edit source]

To prevent ototoxicity, healthcare providers should carefully monitor patients who are taking ototoxic medications. Dosing adjustments or alternative medications may be considered to minimize the risk of hearing or balance problems. Patients should also report any changes in their hearing or balance to their healthcare provider promptly.


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Contributors: Prab R. Tumpati, MD