Pancreatic elastase

Pancreatic elastase is a form of elastase which is produced in the pancreas. It is an enzyme that specifically breaks down elastin, a protein that gives elasticity to tissues and organs.

Function

Pancreatic elastase is secreted by the pancreas into the digestive system. It is involved in the digestion of proteins, breaking them down into smaller peptides and amino acids that can be absorbed and used by the body. The enzyme is particularly effective at breaking down elastin, a protein found in connective tissue.

Clinical significance

Measurement of pancreatic elastase in stool samples is used as a marker of pancreatic function. Low levels of the enzyme in the stool can indicate pancreatic insufficiency, a condition where the pancreas does not produce enough digestive enzymes. This can be seen in conditions such as chronic pancreatitis, cystic fibrosis, and pancreatic cancer.

See also

• Elastase
• Pancreas
• Digestive enzyme
• Pancreatic insufficiency

References

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