Paramethoxyethylamphetamine

Paramethoxyethylamphetamine (PMEA) is a psychoactive drug and research chemical belonging to the amphetamine class of compounds. It is closely related to other substances such as paramethoxyamphetamine (PMA) and methylenedioxymethamphetamine (MDMA), sharing similar chemical structures and effects. PMEA has been found to act as a serotonin, dopamine, and norepinephrine releasing agent, which contributes to its psychoactive properties. However, compared to its more famous relatives like MDMA, PMEA is less potent and has been less widely studied or used recreationally.

The synthesis and pharmacological effects of PMEA were first described in scientific literature in the late 20th century. Since then, it has been encountered sporadically in the illicit drug market, often misrepresented as MDMA or other more popular empathogens. This misidentification can lead to dangerous consequences due to the differing potencies and effects of these substances.

Effects

The effects of PMEA, as reported by users, can include euphoria, increased empathy and sociability, mild hallucinations, and altered sensory perception. However, due to its lower potency, the effects are generally less intense than those of MDMA. The risk of adverse effects, including neurotoxicity, hyperthermia, and cardiovascular problems, is also present, especially when taken in high doses or in combination with other substances.

Health Risks

The health risks associated with PMEA are not well-documented due to its rarity and limited use. However, as with other amphetamines, potential risks include addiction, serotonin syndrome, and long-term neurotoxic effects. The lack of research and information on PMEA makes it particularly risky, as the full extent of its effects and interactions with other drugs are not well understood.

Legal Status

The legal status of PMEA varies by country, but it is often controlled under laws targeting designer drugs and analogs of controlled substances. In many jurisdictions, it is illegal to manufacture, distribute, or possess PMEA without a license.

See Also

• Paramethoxyamphetamine (PMA)
• Methylenedioxymethamphetamine (MDMA)
• Psychoactive drug
• Research chemical