Phthalic acid

From WikiMD's Food, Medicine & Wellness Encyclopedia

Phthalic acid is an aromatic dicarboxylic acid, with formula C6H4(COOH)2. It is an isomer of isophthalic acid and terephthalic acid. Phthalic acid is an industrially important chemical used primarily in the production of plasticizers for plastics.

History[edit | edit source]

Phthalic acid was first obtained by French chemist Auguste Laurent in 1836 by oxidizing naphthalene in the presence of aluminium chloride. However, it was not until 1863 that German chemist August Wilhelm von Hofmann correctly identified the formula of phthalic acid.

Production[edit | edit source]

Phthalic acid is produced by the catalytic oxidation of naphthalene or ortho-xylene directly by oxygen in the presence of a vanadium pentoxide catalyst.

Uses[edit | edit source]

The primary use of phthalic acid is in the production of plasticizers, specifically phthalates, that increase the flexibility, transparency, durability, and longevity of plastics. It is also used as a precursor to other chemicals such as phthalimide and phthalanilic acid.

Health and Safety[edit | edit source]

Phthalic acid is a relatively weak acid and is generally safe to handle. However, it can cause irritation to the skin and eyes. Long-term exposure to phthalic acid can lead to more serious health problems such as respiratory disorders and endocrine disruption.

Environmental Impact[edit | edit source]

Phthalic acid and its derivatives have been detected in the environment due to their widespread use in plastics and other industrial processes. They are known to be endocrine disruptors, and their potential effects on human health and the environment are the subject of ongoing research.

See Also[edit | edit source]

Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.


Contributors: Prab R. Tumpati, MD