Primary triad

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Primary Triad refers to a conceptual framework in the field of emergency medicine and trauma care that emphasizes the immediate recognition and treatment of three critical conditions that are the most common preventable causes of death in trauma patients. These conditions are: hypothermia, acidosis, and coagulopathy. This triad is also known as the "lethal triad" or "trauma triad of death" due to its significant impact on mortality if not promptly addressed.

Hypothermia[edit | edit source]

Hypothermia occurs when the body loses heat faster than it can produce heat, causing a dangerously low body temperature. In trauma patients, hypothermia can be exacerbated by exposure to cold environments, loss of blood, or shock. It impairs the body's clotting ability, leading to increased bleeding and further exacerbating coagulopathy.

Acidosis[edit | edit source]

Acidosis refers to the condition where there is too much acid in the body fluids, which can occur in trauma patients due to shock or as a result of severe blood loss. Lactic acid builds up when oxygen delivery to tissues is compromised, leading to a decrease in the pH of the blood. This acidic environment can impair various cellular functions, including clot formation, further complicating the management of trauma patients.

Coagulopathy[edit | edit source]

Coagulopathy is a condition where the blood's ability to clot is impaired, leading to excessive bleeding. In the context of the primary triad, coagulopathy can be a result of or exacerbated by hypothermia and acidosis. It is a critical condition that needs to be managed promptly to prevent significant blood loss and further deterioration of the patient's condition.

Management[edit | edit source]

The management of the primary triad involves a multidisciplinary approach that includes rapid assessment, prevention, and correction of these conditions. Strategies include warming the patient to combat hypothermia, administering fluids and blood products to correct acidosis and improve perfusion, and using medications or blood products to address coagulopathy. The goal is to stabilize the patient and prevent the exacerbation of these conditions, which can lead to increased mortality.

Conclusion[edit | edit source]

The primary triad is a critical concept in trauma care that highlights the interconnectedness of hypothermia, acidosis, and coagulopathy in contributing to trauma mortality. Early recognition and aggressive management of these conditions are essential in improving outcomes for trauma patients.


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Contributors: Prab R. Tumpati, MD