Profens

Profens are a class of non-steroidal anti-inflammatory drugs (NSAIDs) that are used to relieve pain and inflammation. They are commonly used in the treatment of conditions such as arthritis, gout, and menstrual pain. Profens work by inhibiting the production of prostaglandins, chemicals in the body that cause inflammation and pain.

Mechanism of Action[edit | edit source]

Profens work by inhibiting the enzyme cyclooxygenase (COX), which is responsible for the production of prostaglandins. There are two types of COX enzymes: COX-1 and COX-2. COX-1 is involved in the production of prostaglandins that protect the stomach lining, while COX-2 is involved in the production of prostaglandins that cause inflammation and pain. Most profens inhibit both COX-1 and COX-2, but some are more selective and primarily inhibit COX-2.

Uses[edit | edit source]

Profens are used to relieve pain and inflammation in a variety of conditions, including:

Arthritis: Profens can help to reduce the pain and inflammation associated with arthritis.
Gout: Profens can help to reduce the pain and inflammation caused by gout.
Menstrual pain: Profens can help to relieve the pain associated with menstrual cramps.
Headache: Profens can be used to relieve the pain of headaches.

Side Effects[edit | edit source]

Like all medications, profens can cause side effects. These may include:

Stomach ulcers: Because profens inhibit the production of prostaglandins that protect the stomach lining, they can cause stomach ulcers.
Kidney damage: Long-term use of profens can cause kidney damage.
Heart problems: Some studies have suggested that long-term use of profens may increase the risk of heart problems.