Protein DEPP

Protein DEPP is a protein that in humans is encoded by the DEPP gene. This protein is involved in various biological processes, including cell proliferation, apoptosis, and stress response.

Function

Protein DEPP, also known as Decidual Protein Induced by Progesterone (DEPP), is a transcription factor that plays a crucial role in the regulation of cell cycle and cell death. It is primarily expressed in the decidua of the uterus during the luteal phase of the menstrual cycle, hence its name.

Structure

The DEPP protein is a small protein of 113 amino acids in length. It contains a single zinc finger domain, which is a common feature of transcription factors. This domain allows the protein to bind to specific sequences of DNA and regulate the transcription of target genes.

Clinical significance

Alterations in the DEPP gene have been associated with various diseases, including cancer, cardiovascular disease, and neurodegenerative disease. For instance, overexpression of DEPP has been observed in several types of cancer, suggesting that it may play a role in tumor progression.

Research

Research on Protein DEPP is ongoing, with studies focusing on its role in cell proliferation and apoptosis, as well as its potential as a therapeutic target in cancer treatment.

File:Protein DEPP structure.jpg

The structure of Protein DEPP, showing the zinc finger domain.

See also

• DEPP gene
• Transcription factor
• Cell cycle
• Apoptosis

References

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