Proto-mitochondrion

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Proto-mitochondrion refers to the ancestral bacterial organism that, through the process of endosymbiosis, gave rise to the mitochondria found in most eukaryotic cells today. This event is a significant milestone in the evolution of life, marking the transition from prokaryotes to eukaryotes.

Origin[edit | edit source]

The proto-mitochondrion is believed to have been a free-living alpha-proteobacteria, a group of bacteria that includes species such as Rhodospirillum rubrum and Rickettsia. The exact species that gave rise to the proto-mitochondrion is not known, but it is thought to have been similar to these extant species.

Endosymbiosis[edit | edit source]

The proto-mitochondrion was engulfed by a primitive eukaryotic cell, a process known as phagocytosis. Instead of being digested, the proto-mitochondrion formed a symbiotic relationship with its host. This event is known as the mitochondrial endosymbiosis event.

Over time, the proto-mitochondrion transferred many of its genes to the host cell's nucleus, a process known as endosymbiotic gene transfer. This resulted in the proto-mitochondrion becoming an integral part of the host cell, eventually evolving into the mitochondrion.

Function[edit | edit source]

The proto-mitochondrion likely provided the host cell with a significant advantage, such as the ability to use oxygen for cellular respiration, which is more efficient than the anaerobic respiration used by most prokaryotes. This would have allowed the host cell to produce more ATP, the main energy currency of the cell.

Evolution[edit | edit source]

The evolution of the proto-mitochondrion into the modern mitochondrion is a complex process that is still not fully understood. It is thought to have involved a series of gradual changes over millions of years, driven by natural selection.

See also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD