RTI-126
RTI-126 is a psychoactive drug and research chemical that was first developed in the 1990s by the Research Triangle Institute (RTI). It is part of a series of compounds known as the RTI compounds, which were created in an attempt to develop a substance that could be used as a cocaine substitute. RTI-126 is a dopamine reuptake inhibitor, meaning it increases the levels of dopamine in the brain by blocking its reuptake into neurons.
Chemistry[edit | edit source]
RTI-126 is a tropane derivative, which is a class of compounds that includes many naturally occurring alkaloids. It is structurally similar to cocaine, but with a different substitution pattern on the tropane ring. The compound is also known as 3β-(4-chlorophenyl)-2β-[3-(4'-methylphenyl)isoxazol-5-yl]tropane or RTI-4229-126.
Pharmacology[edit | edit source]
As a dopamine reuptake inhibitor, RTI-126 increases the levels of dopamine in the brain. Dopamine is a neurotransmitter that plays a key role in reward, motivation, and motor control. By blocking the reuptake of dopamine, RTI-126 can produce effects similar to those of cocaine, including increased energy, euphoria, and increased alertness.
However, unlike cocaine, RTI-126 does not have a significant effect on the reuptake of norepinephrine or serotonin, which may result in a different side effect profile. The exact effects of RTI-126 in humans are not well-studied, as the compound is primarily used as a research chemical.
Legal Status[edit | edit source]
RTI-126 is not currently controlled under the United Nations Convention on Psychotropic Substances, but it may be considered illegal in some countries under analogue laws. In the United States, RTI-126 is not specifically listed as a controlled substance, but it could potentially be considered a controlled substance analogue.
See Also[edit | edit source]
RTI-126 Resources | ||
---|---|---|
|
|
Translate to: East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD