SERPINB10

SERPINB10 is a protein that in humans is encoded by the SERPINB10 gene. It is a member of the serpin superfamily of serine protease inhibitors.

Function

SERPINB10 is known to inhibit proteases, which are enzymes that increase the rate of chemical reactions in the body. Specifically, SERPINB10 inhibits trypsin, plasmin, and cathepsin G, which are involved in various physiological processes such as digestion and blood clotting.

Clinical significance

Alterations in the SERPINB10 gene have been associated with certain medical conditions. For example, mutations in this gene have been linked to cancer, particularly lung cancer and breast cancer. This is because SERPINB10 plays a role in controlling cell growth and preventing tumor formation.

Research

Research is ongoing to better understand the role of SERPINB10 in health and disease. For instance, studies are being conducted to determine how mutations in the SERPINB10 gene contribute to cancer development and progression.

See also

• Serpin
• Protease
• Cancer

References

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