Serrated polyposis syndrome

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Serrated polyposis syndrome
File:Hyperplastic Polyp of the Rectum (14060044206).jpg Hyperplastic polyp of the rectum
Synonyms	Hyperplastic polyposis syndrome
Pronounce	N/A
Specialty	N/A
Symptoms	Multiple serrated polyps in the colon
Complications	Increased risk of colorectal cancer
Onset	Typically diagnosed in adulthood
Duration	Chronic
Types	N/A
Causes	Unknown, possibly genetic factors
Risks	Family history of colorectal cancer
Diagnosis	Colonoscopy and histological examination
Differential diagnosis	Familial adenomatous polyposis, Lynch syndrome
Prevention	Regular colonoscopy screenings
Treatment	Surveillance and polypectomy
Medication	N/A
Prognosis	Variable, depends on polyp burden and cancer development
Frequency	Rare, exact prevalence unknown
Deaths	N/A

File:Traditional serrated adenoma intermed mag.jpg

Serrated polyposis syndrome

File:Sessile serrated adenoma 3 very high mag.jpg

Serrated polyposis syndrome

Serrated Polyposis Syndrome (SPS) is a medical condition characterized by the presence of multiple serrated polyps in the colon and rectum. It is a rare condition, but it is associated with an increased risk of developing colorectal cancer.

Definition

Serrated Polyposis Syndrome is defined by the World Health Organization (WHO) as either: having at least five serrated polyps proximal to the sigmoid colon with two or more of these being larger than 10mm; or having any number of serrated polyps occurring proximal to the sigmoid colon in an individual who has a first-degree relative with serrated polyposis; or having more than 20 serrated polyps of any size distributed throughout the colon.

Symptoms

Most people with Serrated Polyposis Syndrome do not have any symptoms. However, some people may experience abdominal pain, diarrhea, constipation, or rectal bleeding.

Diagnosis

The diagnosis of Serrated Polyposis Syndrome is made by colonoscopy, which allows the doctor to see the polyps in the colon and rectum. The polyps are then removed and examined under a microscope to confirm the diagnosis.

Treatment

The treatment for Serrated Polyposis Syndrome involves regular colonoscopies to monitor for the development of new polyps and to remove any that are found. In some cases, surgery may be required to remove larger polyps or sections of the colon.

Prognosis

With regular monitoring and treatment, the prognosis for people with Serrated Polyposis Syndrome is generally good. However, there is an increased risk of developing colorectal cancer, so regular check-ups are important.

See Also

• Colorectal cancer
• Colonoscopy
• Polyp
• Sigmoid colon